| Institution | Research Niche Area |
| University of Limpopo | Theory-based public health intervention research |
| Nelson Mandela Metropolitan University | Building a biodiversity-based economy in the Eastern Cape |
| University of Stellenbosch | Integrative skeletal muscle biology |
| Molecular and cellular processes in cardiovascular degeneration: Strategies for prevention and protection |
| University of Johannesburg | Carbon nano-materials science and engineering |
| University of Kwazulu-Natal | New Approaches to Intransigent health and development problems for children living in poverty |
| UNISA | Ecotoxicology, bio-organic and natural products |
| North-West University | The cultural dynamics of water in Southern Africa |
| Population and health |
| University of the Western Cape | Practices and ideologies of multilingualism |