The South African Centre for Epidemiological Modelling and Analysis (SACEMA), directed by Professor Frank Tanser, is an internationally recognised research centre based at Stellenbosch University. Established in 2006 as a DSTI-NRF Centre of Excellence, SACEMA conducts world-leading research in mathematical and statistical modelling to inform evidence-based public health policy. Its research focuses on HIV, tuberculosis, cervical cancer, antimicrobial resistance, and emerging infectious diseases. SACEMA has made a significant contribution to strengthening public health and informing policy through its evidence-based research. The work has had a tangible impact on public health policy development and implementation, supporting more effective health interventions and outcomes both nationally and internationally.

SACEMA’s work has directly informed South Africa’s HIV Test and Treat policy, the National COVID-19 Epi Model, national tuberculosis strategies, and global HIV surveillance methods adopted by the World Health Organization (WHO), UNAIDS, and the US Centres for Disease Control and Prevention (CDC). SACEMA has made a significant contribution to capacity development by supporting nearly 200 postgraduate students; training more than 850 participants through international modelling clinics, and establishing the Policy Modelling Fellowship, which equips African scientists to provide policy-relevant decision support to Ministries of Health across the continent. Furthermore, Prof Tanser’s leadership as Director of SACEMA reflects his role in guiding and enabling research that has delivered substantial public value. Through its research excellence and policy engagement, SACEMA continues to improve public health outcomes in South Africa and globally. Its work provides a compelling example of how scientific evidence can shape policy and practice, resulting in meaningful societal benefit.